BDBM50214925 5-[1-biphenyl-3-yl-meth-(Z)-ylidene]-10-methoxy-2,2,4-trimethyl-2,4a,5,12a-tetrahydro-1H-6-oxa-1-aza-chrysen-9-ol::CHEMBL231770
SMILES COc1c(O)ccc2O\C(=C/c3cccc(c3)-c3ccccc3)C3=C(C=CC4NC(C)(C)C=C(C)C34)c12
InChI Key InChIKey=DDLPDJJVTVQHQU-VEILYXNESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50214925
Affinity DataKi: 7.20nMAssay Description:Displacement of radiolabeled dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Antagonist activity at GR assessed as inhibition of dexamethasone-induced GRE activationMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at GR by GRE activation assay relative to dexamethasoneMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Activity at GR assessed as repression of TNFalpha and IL 1beta induced E-selectin responseMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at GR by GRE activation assayMore data for this Ligand-Target Pair