BDBM50215325 (3R,4R)-1-(pyrimidin-4-yl)-4-(2,4,5-trifluorophenyl)piperidin-3-aminium 2,2,2-trifluoroacetate::CHEMBL230984

SMILES [NH3+][C@H]1CN(CC[C@@H]1c1cc(F)c(F)cc1F)c1ccncn1

InChI Key InChIKey=AIHJWXVXFBJARD-OTYXRUKQSA-O

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50215325   

TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215325((3R,4R)-1-(pyrimidin-4-yl)-4-(2,4,5-trifluoropheny...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215325((3R,4R)-1-(pyrimidin-4-yl)-4-(2,4,5-trifluoropheny...)
Affinity DataIC50:  37nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215325((3R,4R)-1-(pyrimidin-4-yl)-4-(2,4,5-trifluoropheny...)
Affinity DataIC50:  2.61E+4nMAssay Description:Inhibition of human ERG potassium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215325((3R,4R)-1-(pyrimidin-4-yl)-4-(2,4,5-trifluoropheny...)
Affinity DataIC50:  6.70E+4nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215325((3R,4R)-1-(pyrimidin-4-yl)-4-(2,4,5-trifluoropheny...)
Affinity DataIC50:  950nMAssay Description:Inhibition of Cyp2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215325((3R,4R)-1-(pyrimidin-4-yl)-4-(2,4,5-trifluoropheny...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed