BDBM50218416 CHEMBL316449

SMILES CC(C)(C)n1nc2c(cn(Cc3cccs3)c3ccccc23)c1=O

InChI Key InChIKey=NRHYEDJAXFBQLY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50218416   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(RAT)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50218416(CHEMBL316449)
Affinity DataIC50:  2.00E+3nMAssay Description:Displacement of [3H]rolipram from high affinity binding site (HARBS) in rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50218416(CHEMBL316449)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory potency against guinea pig ventricular phosphodiesterase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50218416(CHEMBL316449)
Affinity DataIC50:  800nMAssay Description:Inhibitory potency against guinea pig ventricular phosphodiesterase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed