BDBM50232860 CHEMBL3125071::US11225469, Compound 23
SMILES Cc1cccc(NC(=S)N2CCN(CC2)c2cccc(c2)C(F)(F)F)c1
InChI Key InChIKey=FHKNYRDPAVRBFO-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50232860
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Whitehead Institute For Biomedical Research
US Patent
Whitehead Institute For Biomedical Research
US Patent
Affinity DataIC50: >2.00E+4nMAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Whitehead Institute For Biomedical Research
US Patent
Whitehead Institute For Biomedical Research
US Patent
Affinity DataIC50: >5.70E+4nMAssay Description:Inhibition of human liver N-terminal His6-tagged PHGDH expressed in Escherichia coli Rosetta (DE3)pLysS using 3 -phosphoglycerate as substarte measur...More data for this Ligand-Target Pair