BDBM50236522 CHEMBL4061698

SMILES COc1ccc(cc1)N(C)C(=O)c1ccc(O)cc1O

InChI Key InChIKey=KNKGXDUKUWVGRE-UHFFFAOYSA-N

Data  5 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50236522   

LigandPNGBDBM50236522(CHEMBL4061698)
Affinity DataKi:  550nMAssay Description:Inhibition of fluorescein-labelled VER160364 binding to PDHK3 (unknown origin) after 90 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236522(CHEMBL4061698)
Affinity DataKi:  1.07E+3nMAssay Description:Inhibition of fluorescein-labelled VER160364 binding to PDHK2 (unknown origin) after 90 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236522(CHEMBL4061698)
Affinity DataKi:  1.27E+3nMAssay Description:Inhibition of fluorescein-labelled VER160364 binding to PDHK4 (unknown origin) after 90 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50236522(CHEMBL4061698)
Affinity DataKi:  1.38E+3nMAssay Description:Displacement of fluorescein-labelled VER160364 from HSP90A (unknown origin) after 90 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236522(CHEMBL4061698)
Affinity DataKi:  1.93E+3nMAssay Description:Inhibition of fluorescein-labelled VER160364 binding to PDHK1 (unknown origin) after 90 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
LigandPNGBDBM50236522(CHEMBL4061698)
Affinity DataIC50: 2.23E+3nMAssay Description:Inhibition of fluorescein-labelled VER160364 binding to PDHK2 (unknown origin) after 90 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50236522(CHEMBL4061698)
Affinity DataIC50: 3.02E+3nMAssay Description:Displacement of fluorescein-labelled VER160364 from HSP90A (unknown origin) after 90 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2019
Entry Details Article
PubMed