BDBM50238800 CHEMBL4101091

SMILES CCN(CC)CCCCNc1ncc2cc(-c3ccccc3Cl)c(=O)n(Cc3cccc(CNC(=O)C=C)c3)c2n1

InChI Key InChIKey=BTTBOQKKUYVCIR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50238800   

TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238800(CHEMBL4101091)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human FGFR4 preincubated for 15 mins followed by peptide substrate addition measured after 3 hrs by caliper capillary electrophoresis m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238800(CHEMBL4101091)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of FGFR1 in HUVEC assessed as reduction in FGF2-induced ERK phosphorylation preincubated for 60 mins followed by FGF2 stimulation for 10 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238800(CHEMBL4101091)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human FGFR3 preincubated for 15 mins followed by peptide substrate addition measured after 3 hrs by caliper capillary electrophoresis m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Principia Biopharma

Curated by ChEMBL
LigandPNGBDBM50238800(CHEMBL4101091)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro antagonist activity against rat prostatic androgen receptor (AR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed