BDBM50241021 CHEMBL4071599

SMILES OCC(CO)(CO)NC(=O)c1ccc2COc3cc(Nc4cc(NC(=O)c5cccs5)c(F)cc4F)ccc3C(=O)c2c1

InChI Key InChIKey=DZTFCXQTDZXUHY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50241021   

TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-Universitaet Tuebingen

Curated by ChEMBL
LigandPNGBDBM50241021(CHEMBL4071599)
Affinity DataIC50: 3nMAssay Description:Inhibition of P38 alpha MAPK (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2019
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-Universitaet Tuebingen

Curated by ChEMBL
LigandPNGBDBM50241021(CHEMBL4071599)
Affinity DataIC50: 107nMAssay Description:Inhibition of P38 alpha MAPK in human whole blood assessed as reduction in TNF-alpha release after 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2019
Entry Details Article
PubMed