BDBM50241035 1-[(1R,2R,4S,5S)-5-carbamimidamido-2,4-bis(2,4-dicarbamimidamidophenoxy)cyclohexyl]guanidine::CHEMBL205548

SMILES [#7]\[#6](-[#7])=[#7]\[#6@@H]-1-[#6]-[#6@H](\[#7]=[#6](\[#7])-[#7])-[#6@H](-[#6]-[#6@H]1-[#8]-c1ccc(cc1\[#7]=[#6](\[#7])-[#7])\[#7]=[#6](\[#7])-[#7])-[#8]-c1ccc(cc1\[#7]=[#6](\[#7])-[#7])\[#7]=[#6](\[#7])-[#7]

InChI Key InChIKey=SWPCXTNDGTURLE-MHGIMSBQSA-N

Data  2 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50241035   

TargetFurin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50241035(1-[(1R,2R,4S,5S)-5-carbamimidamido-2,4-bis(2,4-dic...)
Affinity DataKi:  169nMAssay Description:Inhibition of Recombinant vaccinia-expressed furin (unknown origin) using Pyr-RTKR-MCA as substrate and measured by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetFurin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50241035(1-[(1R,2R,4S,5S)-5-carbamimidamido-2,4-bis(2,4-dic...)
Affinity DataKi:  169nMAssay Description:Inhibition of human recombinant furin-dependent anthrax protective antigen processingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
University of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50241035(1-[(1R,2R,4S,5S)-5-carbamimidamido-2,4-bis(2,4-dic...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of dengue virus-3 NS2B-NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(WNV)
Australian National University Canberra

Curated by ChEMBL
LigandPNGBDBM50241035(1-[(1R,2R,4S,5S)-5-carbamimidamido-2,4-bis(2,4-dic...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity against cell free dihydrofolate redutase (DHFR) from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
University of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50241035(1-[(1R,2R,4S,5S)-5-carbamimidamido-2,4-bis(2,4-dic...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of dengue virus-4 NS2B-NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
University of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50241035(1-[(1R,2R,4S,5S)-5-carbamimidamido-2,4-bis(2,4-dic...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of dengue virus-2 NS2B-NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Dengue virus 2)
University of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50241035(1-[(1R,2R,4S,5S)-5-carbamimidamido-2,4-bis(2,4-dic...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of dengue virus-1 NS2B-NS3 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed