BDBM50244081 (1S,5S)-1-(5-fluorobenzo[b]thiophen-2-yl)-3-aza-bicyclo[3.1.0]hexane::CHEMBL444992

SMILES Fc1ccc2sc(cc2c1)[C@@]12C[C@@H]1CNC2

InChI Key InChIKey=CFWHOTMOLFXUOB-NOZJJQNGSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50244081   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50244081((1S,5S)-1-(5-fluorobenzo[b]thiophen-2-yl)-3-aza-bi...)
Affinity DataIC50:  33nMAssay Description:Inhibition of serotonin uptake at SERT in rat brain synaptosomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50244081((1S,5S)-1-(5-fluorobenzo[b]thiophen-2-yl)-3-aza-bi...)
Affinity DataIC50:  420nMAssay Description:Inhibition of dopamine uptake at cloned DAT in rat brain synaptosomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50244081((1S,5S)-1-(5-fluorobenzo[b]thiophen-2-yl)-3-aza-bi...)
Affinity DataIC50:  67nMAssay Description:Inhibition of norepinephrine uptake at NET in rat brain synaptosomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed