BDBM50244338 4-(((1-methyl-1H-benzo[d]imidazol-2-yl)(4-(trifluoromethoxy)phenyl)amino)methyl)-N-(1H-tetrazol-5-yl)benzamide::CHEMBL469903

SMILES Cn1c(nc2ccccc12)N(Cc1ccc(cc1)C(=O)Nc1nnn[nH]1)c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=VXTYNEMWNNCRQD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50244338   

TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50244338(4-(((1-methyl-1H-benzo[d]imidazol-2-yl)(4-(trifluo...)
Affinity DataIC50: 90nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50244338(4-(((1-methyl-1H-benzo[d]imidazol-2-yl)(4-(trifluo...)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity against human GCGR expressed in CHO cells assessed as glucagon-induced cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed