BDBM50244376 CHEMBL488682::trans-(R)-3-(4-(((4-tert-butylcyclohexyl)(1-methyl-1H-benzo[d]imidazol-2-yl)amino)methyl)benzamido)-2-hydroxypropanoic acid

SMILES Cn1c(nc2ccccc12)N(Cc1ccc(cc1)C(=O)NC[C@@H](O)C(O)=O)[C@H]1CC[C@@H](CC1)C(C)(C)C

InChI Key InChIKey=ODDRNPBPMNSRPS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50244376   

TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50244376(trans-(R)-3-(4-(((4-tert-butylcyclohexyl)(1-methyl...)
Affinity DataIC50: 14nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50244376(trans-(R)-3-(4-(((4-tert-butylcyclohexyl)(1-methyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity against human GCGR expressed in CHO cells assessed as glucagon-induced cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed