BDBM50246361 CHEMBL455195::N-(5-((5-tert-butyloxazol-2-yl)methylthio)thiazol-2-yl)-2-ethylpiperidine-4-carboxamide

SMILES CCC1CC(CCN1)C(=O)Nc1ncc(SCc2ncc(o2)C(C)(C)C)s1

InChI Key InChIKey=WBUZWMNIWAQICA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246361   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246361(CHEMBL455195 | N-(5-((5-tert-butyloxazol-2-yl)meth...)
Affinity DataIC50:  3nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246361(CHEMBL455195 | N-(5-((5-tert-butyloxazol-2-yl)meth...)
Affinity DataIC50:  680nMAssay Description:Inhibition of CDK9-mediated RNA pol 2 phosphorylation at ser2 in human HCT116 cells after 16 hrs by HCS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed