BDBM50250289 CHEMBL4090080

SMILES COC(=O)c1ccc(CN2CCC(CC2)NC(=O)c2ccc(Cl)cc2Cl)cc1

InChI Key InChIKey=FUZAVUNXERGYBW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50250289   

TargetSodium- and chloride-dependent betaine transporter(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250289(CHEMBL4090080)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BGT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250289(CHEMBL4090080)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human GAT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250289(CHEMBL4090080)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human GAT3 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 2(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250289(CHEMBL4090080)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human GAT2 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed