BDBM50250319 CHEMBL4071982

SMILES Clc1ccc(C(=O)NC2CCN(C\C=C\c3ccccc3)CC2)c(Cl)c1

InChI Key InChIKey=BXIRJEUENUYXJG-QPJJXVBHSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50250319   

TargetSodium- and chloride-dependent betaine transporter(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250319(CHEMBL4071982)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BGT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250319(CHEMBL4071982)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human GAT3 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250319(CHEMBL4071982)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human GAT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 2(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250319(CHEMBL4071982)
Affinity DataIC50: >1.00E+5nMAssay Description:Binding potency for nAChR subtype Alpha-1-beta-1-delta-gamma (torpedo)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed