BDBM50258873 (R)-3-methyl-2-(4'-((3-methylquinolin-2-yloxy)methyl)biphenyl-4-ylsulfonamido)butanoic acid::CHEMBL468511

SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(COc2nc3ccccc3cc2C)cc1)C(O)=O

InChI Key InChIKey=CIOOPYAGXLBCTE-AREMUKBSSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50258873   

TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50258873((R)-3-methyl-2-(4'-((3-methylquinolin-2-yloxy)meth...)
Affinity DataIC50:  200nMAssay Description:Inhibition of aggrecanase1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed