BDBM50259397 CHEMBL3084549::endo-N-(8-(bis(2-chlorophenyl)methyl)-3-(pyridin-2-yl)-8-azabicyclo[3.2.1]octan-3-yl)acetamide

SMILES [H][C@]12CC[C@]([H])(C[C@](C1)(NC(C)=O)c1ccccn1)N2C(c1ccccc1Cl)c1ccccc1Cl

InChI Key InChIKey=VQBNHSQWESCIPZ-WOJBJXKFSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50259397   

TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259397(CHEMBL3084549 | endo-N-(8-(bis(2-chlorophenyl)meth...)
Affinity DataKi:  6nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human cloned ORL1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259397(CHEMBL3084549 | endo-N-(8-(bis(2-chlorophenyl)meth...)
Affinity DataKi:  312nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259397(CHEMBL3084549 | endo-N-(8-(bis(2-chlorophenyl)meth...)
Affinity DataEC50:  1.93E+3nMAssay Description:Agonist activity at human cloned ORL1 receptor assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259397(CHEMBL3084549 | endo-N-(8-(bis(2-chlorophenyl)meth...)
Affinity DataEC50:  1.93E+3nMAssay Description:Agonist activity at human mu opioid assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed