BDBM50264502 CHEMBL4083010

SMILES Cc1ccc2cccc(S)c2n1

InChI Key InChIKey=DUIAZPVQMPQZSK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50264502   

TargetCOP9 signalosome complex subunit 5(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50264502(CHEMBL4083010)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CSN5 (unknown origin) using SCFskp2-Nedd8OG as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target26S proteasome non-ATPase regulatory subunit 14(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50264502(CHEMBL4083010)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50264502(CHEMBL4083010)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of recombinant human MMP2 catalytic domain (Tyr110 to Asp452 residues) expressed in yeast using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2.AcOH a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed