BDBM50264536 CHEMBL4076981::US10005735, Table 1.4

SMILES CSc1cccc2cccnc12

InChI Key InChIKey=MDHLUPGPSGUEAV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50264536   

Target26S proteasome non-ATPase regulatory subunit 14(Human)
California Institute of Technology

US Patent
LigandPNGBDBM50264536(US10005735, Table 1.4 | CHEMBL4076981)
Affinity DataIC50: 1.00E+5nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

Target26S proteasome non-ATPase regulatory subunit 14(Human)
California Institute of Technology

US Patent
LigandPNGBDBM50264536(US10005735, Table 1.4 | CHEMBL4076981)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed