BDBM50272307 4-(2-(1-methyl-4-phenyl-1H-imidazol-5-ylamino)ethyl)pyrimidin-2-amine::CHEMBL499863

SMILES Cn1cnc(c1NCCc1ccnc(N)n1)-c1ccccc1

InChI Key InChIKey=PLGZDDWOIXOUIE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50272307   

TargetAngiopoietin-1 receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272307(4-(2-(1-methyl-4-phenyl-1H-imidazol-5-ylamino)ethy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant Tie2 expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272307(4-(2-(1-methyl-4-phenyl-1H-imidazol-5-ylamino)ethy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant Flt1 expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272307(4-(2-(1-methyl-4-phenyl-1H-imidazol-5-ylamino)ethy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant KDR expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed