BDBM50278138 CHEMBL471054::N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)quinoline-3-carboxamide

SMILES O=C(NCCN1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccc2ccccc2n1

InChI Key InChIKey=FPAYIMLIUXRMMC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50278138   

TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50278138(CHEMBL471054 | N-(2-(4-oxo-1-phenyl-1,3,8-triazasp...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of PLD1 in human Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50278138(CHEMBL471054 | N-(2-(4-oxo-1-phenyl-1,3,8-triazasp...)
Affinity DataIC50:  500nMAssay Description:Inhibition of PLD2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50278138(CHEMBL471054 | N-(2-(4-oxo-1-phenyl-1,3,8-triazasp...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of PLD1 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50278138(CHEMBL471054 | N-(2-(4-oxo-1-phenyl-1,3,8-triazasp...)
Affinity DataIC50:  90nMAssay Description:Inhibition of GFP-labeled PLD2 in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed