BDBM50280451 CHEMBL4162197

SMILES COc1cnc(cn1)C(=O)Nc1ccc(F)c(c1)[C@@]1(C)N=C(N)CO[C@H]1C(F)F

InChI Key InChIKey=UTGAHEBFVPQOGI-MAUKXSAKSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50280451   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50280451(CHEMBL4162197)
Affinity DataIC50: >1.00E+4nMAssay Description:In vivo inhibition of leutenising hormone in rats.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50280451(CHEMBL4162197)
Affinity DataIC50:  11nMAssay Description:Inhibition of L1210 leukemia thymidylate synthase (TS) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50280451(CHEMBL4162197)
Affinity DataIC50:  4.90nMAssay Description:In vivo inhibition of leutenising hormone in rats.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed