BDBM50287987 CHEMBL4167230

SMILES NC(=N)Nc1cccc(c1)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)NCCc1c[nH]c2ccccc12

InChI Key InChIKey=KTPKPDHZXPMGRV-IBGZPJMESA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50287987   

TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50287987(CHEMBL4167230)
Affinity DataIC50:  4nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Mdm4(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50287987(CHEMBL4167230)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of p53 from MDM4 in human SHSY-5Y cells incubated for 10 mins by sandwich ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50287987(CHEMBL4167230)
Affinity DataIC50:  308nMAssay Description:Displacement of p53 from MDM2 in human U87MG cells incubated for 10 mins by sandwich ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50287987(CHEMBL4167230)
Affinity DataIC50:  36nMAssay Description:Inhibition of fibronectin binding to soluble alpha5beta1 integrin (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed