BDBM50303650 (R)-2-[4-(4-Chlorophenoxy)phenoxymethyl]pyrrolidine::CHEMBL566225

SMILES Clc1ccc(Oc2ccc(OC[C@H]3CCCN3)cc2)cc1

InChI Key InChIKey=OUVSEVIBPWQASX-CQSZACIVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303650   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303650((R)-2-[4-(4-Chlorophenoxy)phenoxymethyl]pyrrolidin...)
Affinity DataIC50:  533nMAssay Description:Inhibition of human LTA4H hydrolysis assessed as inhibition of Ca2+ ionophore-stimulated LTB4 formation in human whole blood by ELISAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303650((R)-2-[4-(4-Chlorophenoxy)phenoxymethyl]pyrrolidin...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed