BDBM50311020 CHEMBL1078453::N-(2-cyanopropan-2-yl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide

SMILES CC(C)(NC(=O)c1ccc(cc1)-c1ccnc(Nc2ccc(cc2)N2CCOCC2)n1)C#N

InChI Key InChIKey=XRZVCGWERZVRNT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311020   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311020(CHEMBL1078453 | N-(2-cyanopropan-2-yl)-4-(2-(4-mor...)
Affinity DataIC50:  3.91E+3nMAssay Description:Inhibition of GST-tagged JAK3 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311020(CHEMBL1078453 | N-(2-cyanopropan-2-yl)-4-(2-(4-mor...)
Affinity DataIC50:  549nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed