BDBM50315447 4,6-dihydroxy-2-((2-methyl-1H-indol-3-yl)methylene)benzofuran-3(2H)-one::CHEMBL1091884

SMILES Cc1[nH]c2ccccc2c1/C=C1\Oc2cc(O)cc(O)c2C1=O

InChI Key InChIKey=DAJDCRRHQWUCDG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315447   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315447BDBM50315447(4,6-dihydroxy-2-((2-methyl-1H-indol-3-yl)methylene...)
Affinity DataIC50: 500nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50315447BDBM50315447(4,6-dihydroxy-2-((2-methyl-1H-indol-3-yl)methylene...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed