BDBM50315450 2-((5-bromo-1H-indol-3-yl)methylene)-4,6-dihydroxybenzofuran-3(2H)-one::CHEMBL1093930

SMILES O=C1/C(=C/c2c[nH]c3ccc(Br)cc23)Oc2cc(O)cc(O)c21

InChI Key InChIKey=JXORKGIIJMDFEJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50315450   

LigandChemical structure of BindingDB Monomer ID 50315450BDBM50315450(2-((5-bromo-1H-indol-3-yl)methylene)-4,6-dihydroxy...)
Affinity DataIC50: 422nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50315450BDBM50315450(2-((5-bromo-1H-indol-3-yl)methylene)-4,6-dihydroxy...)
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315450BDBM50315450(2-((5-bromo-1H-indol-3-yl)methylene)-4,6-dihydroxy...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed