BDBM50315728 3-(4-Morpholin-4-yl-5H-pyrrolo[3,2-d]pyrimidin-2-yl)aniline::CHEMBL1092556

SMILES Nc1cccc(-c2nc(N3CCOCC3)c3[nH]ccc3n2)c1

InChI Key InChIKey=HFMDLESHJZWMPX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315728   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315728BDBM50315728(3-(4-Morpholin-4-yl-5H-pyrrolo[3,2-d]pyrimidin-2-y...)
Affinity DataIC50: 430nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50315728BDBM50315728(3-(4-Morpholin-4-yl-5H-pyrrolo[3,2-d]pyrimidin-2-y...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed