BDBM50315735 3-{7-[1-(4-Fluorobenzyl)piperidin-4-yl]-4-morpholin-4-yl-5Hpyrrolo[3,2-d]pyrimidin-2-yl}phenol::CHEMBL1088832

SMILES Oc1cccc(-c2nc(N3CCOCC3)c3[nH]cc(C4CCN(Cc5ccc(F)cc5)CC4)c3n2)c1

InChI Key InChIKey=GGFPPLTUSBYFPC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315735   

LigandChemical structure of BindingDB Monomer ID 50315735BDBM50315735(3-{7-[1-(4-Fluorobenzyl)piperidin-4-yl]-4-morpholi...)
Affinity DataIC50: 178nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315735BDBM50315735(3-{7-[1-(4-Fluorobenzyl)piperidin-4-yl]-4-morpholi...)
Affinity DataIC50: 3.65E+3nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed