BDBM50324100 CHEMBL1214830::N-((Benzofuran-2-yl)methyl)-N'-(4'-methoxybenzyl)piperazine

SMILES COc1ccc(CN2CCN(Cc3cc4ccccc4o3)CC2)cc1

InChI Key InChIKey=YCWVGXHIBUBRER-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50324100   

TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50324100(CHEMBL1214830 | N-((Benzofuran-2-yl)methyl)-N'-(4'...)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50324100(CHEMBL1214830 | N-((Benzofuran-2-yl)methyl)-N'-(4'...)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]pentazocine from sigma1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50324100(CHEMBL1214830 | N-((Benzofuran-2-yl)methyl)-N'-(4'...)
Affinity DataKi:  15nMAssay Description:Binding affinity to 5HT2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50324100(CHEMBL1214830 | N-((Benzofuran-2-yl)methyl)-N'-(4'...)
Affinity DataKi:  2.19E+3nMAssay Description:Binding affinity to 5HT1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50324100(CHEMBL1214830 | N-((Benzofuran-2-yl)methyl)-N'-(4'...)
Affinity DataKi:  2.70E+3nMAssay Description:Binding affinity to dopamine D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed