BDBM50329543 (R)-2-amino-4-(4-(difluoromethoxy)phenyl)-1-methyl-4-(3-(prop-1-ynyl)phenyl)-1H-imidazol-5(4H)-one::CHEMBL1270934
SMILES CC#Cc1cccc(c1)[C@]1(N=C(N)N(C)C1=O)c1ccc(OC(F)F)cc1
InChI Key InChIKey=RIIMHERUTFJZHJ-HXUWFJFHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50329543
Affinity DataEC50: 70nMAssay Description:Inhibition of human recombinant BACE1 expressed in CHO cells assessed as reduction in amyloid beta level by sandwich ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of renin by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of BACE2 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.12E+3nMAssay Description:Inhibition of cathepsin D by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair