BDBM50332945 CHEMBL1232074::N-hydroxy-2-(4-methoxy-N-(2-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)ethyl)phenylsulfonamido)acetamide::N-hydroxy-2-{[(4-methoxyphenyl)sulfonyl](2-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}ethyl)amino}acetamide

SMILES COc1ccc(cc1)S(=O)(=O)N(CCO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)CC(=O)NO

InChI Key InChIKey=RBZQWZODGBMNHX-USACIQFYSA-N

Data  9 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50332945   

TargetCollagenase 3(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332945(CHEMBL1232074 | N-hydroxy-2-(4-methoxy-N-(2-((2R,3...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of MMP13 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332945(CHEMBL1232074 | N-hydroxy-2-(4-methoxy-N-(2-((2R,3...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of MMP-13 catalytic domain (unknown origin) assessed as inhibition of hydrolysis of Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Protera

Curated by ChEMBL
LigandPNGBDBM50332945(CHEMBL1232074 | N-hydroxy-2-(4-methoxy-N-(2-((2R,3...)
Affinity DataKi:  9.10nMAssay Description:Inhibition of MMP8 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50332945(CHEMBL1232074 | N-hydroxy-2-(4-methoxy-N-(2-((2R,3...)
Affinity DataKi:  14nMAssay Description:Inhibition of MMP-12 catalytic domain (unknown origin) assessed as inhibition of hydrolysis of Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate measured...More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50332945(CHEMBL1232074 | N-hydroxy-2-(4-methoxy-N-(2-((2R,3...)
Affinity DataKi:  14.3nMAssay Description:Inhibition of MMP12 by fluorimetric assayMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50332945(CHEMBL1232074 | N-hydroxy-2-(4-methoxy-N-(2-((2R,3...)
Affinity DataKi:  286nMAssay Description:Inhibition of MMP-1 catalytic domain (unknown origin) assessed as inhibition of hydrolysis of Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50332945(CHEMBL1232074 | N-hydroxy-2-(4-methoxy-N-(2-((2R,3...)
Affinity DataKi:  286nMAssay Description:Inhibition of MMP1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50332945(CHEMBL1232074 | N-hydroxy-2-(4-methoxy-N-(2-((2R,3...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of MMP-7 catalytic domain (unknown origin) assessed as inhibition of hydrolysis of Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50332945(CHEMBL1232074 | N-hydroxy-2-(4-methoxy-N-(2-((2R,3...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of MMP7 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed