BDBM50338273 CHEMBL1681997::ethyl 4-ethynyl-2-(2-(4-methoxyphenyl)acetamido)thiophene-3-carboxylate

SMILES CCOC(=O)c1c(NC(=O)Cc2ccc(OC)cc2)scc1C#C

InChI Key InChIKey=DUBZBFMLYCNCJW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50338273   

TargetMitogen-activated protein kinase 8(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338273BDBM50338273(ethyl 4-ethynyl-2-(2-(4-methoxyphenyl)acetamido)th...)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of recombinant JNK1 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338273BDBM50338273(ethyl 4-ethynyl-2-(2-(4-methoxyphenyl)acetamido)th...)
Affinity DataIC50: 3.02E+3nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338273BDBM50338273(ethyl 4-ethynyl-2-(2-(4-methoxyphenyl)acetamido)th...)
Affinity DataIC50: 2.84E+4nMAssay Description:Inhibition of recombinant JNK2 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed