BDBM50341377 3-(2-chlorophenyl)-7-[(trans-4-hydroxycyclohexyl)amino]-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one::CHEMBL1235713::trans-3-(2-chlorophenyl)-7-(4-hydroxycyclohexylamino)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one

SMILES O=C1Nc2nc(N[C@H]3CC[C@H](O)CC3)ncc2CN1c1ccccc1Cl

InChI Key InChIKey=NSHBSERFNQQOCC-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341377   

TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341377BDBM50341377(3-(2-chlorophenyl)-7-[(trans-4-hydroxycyclohexyl)a...)
Affinity DataKd:  32nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341377BDBM50341377(3-(2-chlorophenyl)-7-[(trans-4-hydroxycyclohexyl)a...)
Affinity DataKd: >2.00E+4nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed