BDBM50343247 CHEMBL1773573::N-(4-(2-Acetamidobenzo[d]thiazol-6-yl)pyrimidin-2-yl)-4-methoxybenzamide

SMILES COc1ccc(cc1)C(=O)Nc1nccc(n1)-c1ccc2nc(NC(C)=O)sc2c1

InChI Key InChIKey=PFNHXNIDPJSOBS-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343247   

LigandChemical structure of BindingDB Monomer ID 50343247BDBM50343247(N-(4-(2-Acetamidobenzo[d]thiazol-6-yl)pyrimidin-2-...)
Affinity DataKi:  3.13E+3nMAssay Description:Inhibition of human PI3Kalpha expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343247BDBM50343247(N-(4-(2-Acetamidobenzo[d]thiazol-6-yl)pyrimidin-2-...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of mTOR assessed as inhibition of 4EBP1 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed