BDBM50343783 1-(4-((R)-7-(2-(Dimethylamino)ethyl)-7-methyl-4-((S)-3-methylmorpholino)-5,7-dihydrofuro[3,4-d]pyrimidin-2-yl)phenyl)-3-ethylurea::CHEMBL1774372

SMILES CCNC(=O)Nc1ccc(cc1)-c1nc2c(CO[C@]2(C)CCN(C)C)c(n1)N1CCOC[C@@H]1C

InChI Key InChIKey=YXCSOVNWVXUYBY-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343783   

TargetSerine/threonine-protein kinase mTOR(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343783BDBM50343783(1-(4-((R)-7-(2-(Dimethylamino)ethyl)-7-methyl-4-((...)
Affinity DataKi:  62nMAssay Description:Inhibition of human recombinant mTOR expressed in insect cells using 4E-BP1 substrate after 30 mins by fluorescence resonance energy transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed