BDBM50352602 CHEMBL1822133

SMILES O=C(Cc1cccc2ncc(F)cc12)Nc1scc(Br)c1-c1nnc[nH]1

InChI Key InChIKey=HDGJMVJJOYGVSR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50352602   

TargetMitogen-activated protein kinase 8(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352602BDBM50352602(CHEMBL1822133)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant JNK1 using ser73 of c-jun as substrate preincubated for 15 mins measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352602BDBM50352602(CHEMBL1822133)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant JNK3 using ser73 of c-jun as substrate preincubated for 15 mins measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352602BDBM50352602(CHEMBL1822133)
Affinity DataIC50: 92nMAssay Description:Inhibition of recombinant JNK2 using ser73 of c-jun as substrate preincubated for 15 mins measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed