BDBM50372954 CHEMBL403178

SMILES Fc1ccc(CC23CN(CCC2=Cc2c(C3)cnn2-c2ccc(F)cc2)S(=O)(=O)Nc2ccccc2)cc1

InChI Key InChIKey=SNMCLYVYUVDBPC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50372954   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Corcept Therapeutics

Curated by ChEMBL
LigandPNGBDBM50372954(CHEMBL403178)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Corcept Therapeutics

Curated by ChEMBL
LigandPNGBDBM50372954(CHEMBL403178)
Affinity DataKi:  68nMAssay Description:Antagonist activity at GR in SW1353/MMTV5 cells assessed as inhibition of dexamethasone-induced luciferase expressionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed