BDBM50375652 CHEMBL408565

SMILES BrC1CCc2[nH]c(\C=C3/C(=O)Nc4ccccc34)cc2C1

InChI Key InChIKey=FIFWWQUQNGQSLH-ZROIWOOFSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50375652   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50375652(CHEMBL408565)
Affinity DataIC50:  1.33E+4nMAssay Description:Inhibition of wild type EGFRChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50375652(CHEMBL408565)
Affinity DataIC50:  920nMAssay Description:Inhibition of bPDGFR in human PAC1 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Mus musculus)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50375652(CHEMBL408565)
Affinity DataIC50:  70nMAssay Description:Inhibition of mouse KDRChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50375652(CHEMBL408565)
Affinity DataIC50:  70nMAssay Description:Inhibition of VEGFR2Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50375652(CHEMBL408565)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of EGFRChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed