BDBM50391508 CHEMBL2147316
SMILES COc1cnc(cn1)-c1ccccc1C(F)(F)CNC(=O)c1ccc(COCC(F)(F)F)nc1
InChI Key InChIKey=VAKSCAGQAFHWEJ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50391508
Affinity DataIC50: 251nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of rat Nav1.7 by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of human Nav1.5More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of human ERG channel by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair