BDBM50391508 CHEMBL2147316

SMILES COc1cnc(cn1)-c1ccccc1C(F)(F)CNC(=O)c1ccc(COCC(F)(F)F)nc1

InChI Key InChIKey=VAKSCAGQAFHWEJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50391508   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50391508(CHEMBL2147316)
Affinity DataIC50:  251nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50391508(CHEMBL2147316)
Affinity DataIC50:  900nMAssay Description:Inhibition of rat Nav1.7 by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50391508(CHEMBL2147316)
Affinity DataIC50:  3.16E+4nMAssay Description:Inhibition of human Nav1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50391508(CHEMBL2147316)
Affinity DataIC50:  2.51E+4nMAssay Description:Inhibition of human ERG channel by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed