BDBM50446981 CHEMBL3116051

SMILES C[C@H](Nc1nc(Nc2cn(C)cn2)c2ccn(C)c2n1)c1ncc(F)cn1

InChI Key InChIKey=IGCWHAZMGYJLQW-JTQLQIEISA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50446981   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50446981(CHEMBL3116051)
Affinity DataIC50:  7.56E+3nMAssay Description:Inhibition of Jak3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50446981(CHEMBL3116051)
Affinity DataIC50:  24nMAssay Description:Inhibition of Jak1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50446981(CHEMBL3116051)
Affinity DataIC50:  27nMAssay Description:Inhibition of Jak2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed