BDBM50467447 CHEMBL4277674

SMILES Oc1ccc(-c2n[nH]cc2-c2ccc(Cl)cc2)c(O)c1O

InChI Key InChIKey=OTCNTHCKKGEUQP-UHFFFAOYSA-N

Data  2 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50467447   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Chongqing University

Curated by ChEMBL

LigandBDBM50467447(CHEMBL4277674)Copy SMILESCopy InChI

Affinity DataEC50:  1.20E+3nMAssay Description:Inhibition of wild type PI3Kalpha (unknown origin) after 40 mins by kinase-Glo reagent based luminescence assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/18/2020
Entry Details Article
Copy BDB DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Chongqing University

Curated by ChEMBL

LigandBDBM50467447(CHEMBL4277674)Copy SMILESCopy InChI

Affinity DataEC50:  1.60E+3nMAssay Description:Inhibition of PI3Kalpha H1047R mutant (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/18/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL