BDBM50482849 CHEMBL1258364

SMILES Cc1cc(cc(F)c1Oc1nc(NC2CCN(CC2)c2cccc(c2)C(N)=O)ncc1Br)C#N

InChI Key InChIKey=DCRLONDGVUVHIO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50482849   

TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Roche R&D Center China

Curated by ChEMBL
LigandPNGBDBM50482849(CHEMBL1258364)
Affinity DataIC50:  6nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche R&D Center China

Curated by ChEMBL
LigandPNGBDBM50482849(CHEMBL1258364)
Affinity DataIC50:  6nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Roche R&D Center China

Curated by ChEMBL
LigandPNGBDBM50482849(CHEMBL1258364)
Affinity DataIC50:  29nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase Y188L mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed