BDBM50506661 CHEMBL4517951

SMILES COC(=O)c1cc(Nc2ncnc3[nH]ccc23)ccc1Br

InChI Key InChIKey=YHDDNFHODNKNQV-UHFFFAOYSA-N

Data  2 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50506661   

TargetTau-tubulin kinase 1(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas-Csic

Curated by ChEMBL
LigandPNGBDBM50506661(CHEMBL4517951)
Affinity DataKd:  4.10E+3nMAssay Description:Binding affinity to phosphorylated TTBK1 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTau-tubulin kinase 2(Homo sapiens (Human))
Csic

Curated by ChEMBL
LigandPNGBDBM50506661(CHEMBL4517951)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of recombinant human TTBK2 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetTau-tubulin kinase 1(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas-Csic

Curated by ChEMBL
LigandPNGBDBM50506661(CHEMBL4517951)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTau-tubulin kinase 1(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas-Csic

Curated by ChEMBL
LigandPNGBDBM50506661(CHEMBL4517951)
Affinity DataKd:  4.10E+3nMAssay Description:Binding affinity to CM5 sensor chip immobilized C-terminal His6/TEV fused-GST-tagged human TTBK1 (14 to 313 residues) expressed in baculovirus infect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB