BDBM50509370 CHEMBL4446434

SMILES COc1cc(Br)cc2[nH]cc(-c3cnc(o3)-c3ccc[nH]3)c12

InChI Key InChIKey=HCBIATVCCJRSKR-UHFFFAOYSA-N

Data  17 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50509370   

TargetSerine/threonine-protein kinase pim-1(Human)
Uit - The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50509370(CHEMBL4446434)
Affinity DataIC50:  900nMAssay Description:Inhibition of PIM1 (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase 17B(Human)
Uit - The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50509370(CHEMBL4446434)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of DRAK2 (unknown origin) expressed in HEK293 cells by NanoLuc-luciferase reporter based intracellular ATP competitiveness assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Human)
Uit - The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50509370(CHEMBL4446434)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of PIM3 (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase SIK3(Human)
Uit - The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50509370(CHEMBL4446434)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of SIK3 (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Uit - The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50509370(CHEMBL4446434)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of TAK1 (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 9(Human)
Uit - The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50509370(CHEMBL4446434)
Affinity DataIC50:  900nMAssay Description:Inhibition of MLK1 (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Uit - The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50509370(CHEMBL4446434)
Affinity DataIC50:  500nMAssay Description:Inhibition of MLK3 (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Uit - The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50509370(CHEMBL4446434)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of RIPK2 (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Human)
Uit - The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50509370(CHEMBL4446434)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Aurora A (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase 17A(Human)
Uit - The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50509370(CHEMBL4446434)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of Alexa Fluor 647-labeled ATP competitive kinase tracer binding to GST-tagged DRAK1 (unknown origin) by FRET based cell free ATP-competit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase 17B(Human)
Uit - The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50509370(CHEMBL4446434)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Alexa Fluor 647-labeled ATP competitive kinase tracer binding to GST-tagged DRAK2 (unknown origin) by FRET based cell free ATP-competit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase 17A(Human)
Uit - The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50509370(CHEMBL4446434)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of DRAK1 (unknown origin) expressed in HEK293 cells by NanoLuc-luciferase reporter based intracellular ATP competitiveness assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 15(Human)
Uit - The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50509370(CHEMBL4446434)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of ERK8 (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B(Human)
Uit - The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50509370(CHEMBL4446434)
Affinity DataIC50:  900nMAssay Description:Inhibition of Aurora B (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Uit - The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50509370(CHEMBL4446434)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of DYRK1A (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 2(Human)
Uit - The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50509370(CHEMBL4446434)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of GCK (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Uit - The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50509370(CHEMBL4446434)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of PIM2 (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed