BDBM50547862 CHEMBL4792402

SMILES CC(=O)Nc1ccc2nc(NC(=O)c3[nH]c(C)c(Cl)c3Cl)sc2c1

InChI Key InChIKey=AAWYAFMPUFDEST-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50547862   

TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50547862(CHEMBL4792402)
Affinity DataIC50:  9.5nMAssay Description:Inhibition of Escherichia coli DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50547862(CHEMBL4792402)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 using supercoiled pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50547862(CHEMBL4792402)
Affinity DataIC50:  400nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed