BDBM50566270 CHEMBL4876319
SMILES CCn1nc(C)cc1C(=O)\N=c1/[nH]c2cc(cc(OCCCN3CCOCC3)c2n1C\C=C\Cn1c2c(OC)cc(cc2[nH]\c1=N/C(=O)c1cc(C)nn1CC)-c1ncn[nH]1)C(N)=O
InChI Key InChIKey=RZBQZKAZIZWIRZ-CMDGGOBGSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50566270
Affinity DataEC50: 240nMAssay Description:Activation of human STING (139 to 379 residues) expressed in THP1-Blue ISG cells incubated for 24 hrs by quanti-blue SEAP reporter gene assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Mus musculus)
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataEC50: 3.95E+4nMAssay Description:Activation of mouse STING expressed in RAW-Lucia ISG cells incubated for 24 hrs by quanti-blue SEAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 240nMAssay Description:Agonist activity at human wild type STINGMore data for this Ligand-Target Pair
Affinity DataEC50: 6.20nMAssay Description:Binding affinity to 6His-tagged human STING measured after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Mus musculus)
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataEC50: 3.95E+4nMAssay Description:Agonist activity at mouse STINGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair