BDBM50566469 CHEMBL4876736

SMILES CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](O)Cc1ccccc1)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O

InChI Key InChIKey=ATMSTELHXVEGAU-HGUOCSJCSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50566469   

TargetGlucagon receptor(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50566469(CHEMBL4876736)
Affinity DataIC50:  9nMAssay Description:Displacement of 125I-glucagon from human GCGR expressed in HEK293 cells membranes incubated for 6 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50566469(CHEMBL4876736)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at human GCGR expressed in HEK293 cells assessed as inhibition of glucogon-induced cAMP productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGastric inhibitory polypeptide receptor(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50566469(CHEMBL4876736)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human GIPR expressed in HEK293 cells assessed as inhibition of GIP-induced cAMP productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Mus musculus)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50566469(CHEMBL4876736)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at mouse GLP1R expressed in CHO-K1 cells assessed as inhibition of GLP1-induced cAMP productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Mus musculus)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50566469(CHEMBL4876736)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at mouse GCGR expressed in CHO-K1 cells assessed as inhibition of glucogon-induced cAMP productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGastric inhibitory polypeptide receptor(Mus musculus)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50566469(CHEMBL4876736)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at mouse GIPR expressed in CHO-K1 cells assessed as inhibition of GIP-induced cAMP productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Indiana University

Curated by ChEMBL
LigandPNGBDBM50566469(CHEMBL4876736)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human GLP-1R expressed in HEK293 cells assessed as inhibition of GLP1-induced cAMP productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed