BDBM50584951 CHEMBL5092589
SMILES NC(=O)c1ccc(Nc2ncc(c(N[C@H]3CC[C@H](O)CC3)n2)C(F)(F)F)cn1
InChI Key InChIKey=WOTJZQMSLYWZGS-HOMQSWHASA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50584951
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Zhejiang University
Curated by ChEMBL
Zhejiang University
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of N-terminal GST tagged human recombinant wild type FLT-3 (564-993 residues) expressed in baculovirus infected Sf21 insect cells using TK...More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Zhejiang University
Curated by ChEMBL
Zhejiang University
Curated by ChEMBL
Affinity DataIC50: 337nMAssay Description:Inhibition of N-terminal GST tagged human recombinant cKit (544 residue) expressed in baculovirus infected Sf21 insect cells using TK peptide as subs...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Zhejiang University
Curated by ChEMBL
Zhejiang University
Curated by ChEMBL
Affinity DataIC50: 9.30nMAssay Description:Inhibition of N-terminal GST tagged human recombinant FLT3 D835Y mutant (564 residue) expressed in baculovirus infected Sf21 insect cells using TK pe...More data for this Ligand-Target Pair