BDBM50590935 CHEMBL5171753

SMILES Nc1ncc2CCCc3[nH]c4ccc(cc4c3-c2n1)-c1ccc(F)cc1

InChI Key InChIKey=PJFCVWLQATZEIU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50590935   

Target1-phosphatidylinositol 3-phosphate 5-kinase(Homo sapiens)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50590935(CHEMBL5171753)
Affinity DataIC50:  9.30nMAssay Description:Inhibition of human GST tagged PIKFYVE (1493 to end residues) expressed in baculovirus-infected Sf9 cells using PI(3)P:PS as substrate incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Homo sapiens)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50590935(CHEMBL5171753)
Affinity DataIC50:  11nMAssay Description:Inhibition of PIKFYVE in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Homo sapiens)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50590935(CHEMBL5171753)
Affinity DataIC50:  11nMAssay Description:Inhibition of PIKFYVE in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed