BDBM50609151 CHEMBL5283456

SMILES CC[C@](C)(O)C#Cc1cc2n(ccc2cn1)-c1ccnc(N)n1

InChI Key InChIKey=ISYRCGISNANONJ-KRWDZBQOSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50609151   

TargetTau-tubulin kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50609151(CHEMBL5283456)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of GST-tagged TTBK1 (1 to 421) (unknown origin) using DNA Topoisomerase 2-alpha-Thr1342 as substrate incubated for 15 mins followed by ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTau-tubulin kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50609151(CHEMBL5283456)
Affinity DataIC50:  42nMAssay Description:Inhibition of TTBK1 in human HEK293T cells incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50609151(CHEMBL5283456)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50609151(CHEMBL5283456)
Affinity DataIC50:  95nMAssay Description:Inhibition of NIK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTau-tubulin kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50609151(CHEMBL5283456)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of TTBK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed